Any Anti depressant that does NOT trigger migraines../ headaches ? am exceptionally sensitive Thanks

Sophie Anne

New member
Joined
Aug 20, 2021
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3
Reason
DX FIBRO
Diagnosis
04/2014
Country
IR
Hello All, I am new here ..and v glad to have joined. I am v sensitive to meds..part of fybro brain. Can tolerate Amytryptilline 10mgs max dose !! affects bowel too much and thats with high fibre fluids and laxative use.

Have tried a lot of anti depressants over the years..cymbalta Duloxetine was the first one to help nerve pain in 2009.
Restarted venleflaxine..v ill on a low dose of it early this year..had 5 great months off same ..but new awful low a few days ago.. sadly headaches affects 1/10..have had to stop it twice because of severity of migraines on Venleflaxine ( Effexor)

It causes horrendous weight gain for me too..a stone a month!! definetely not good for the morale or fybro.
Thanks for Your time 😊
 

sunkacola

Very helpful member
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Dec 2, 2016
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1,508
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DX FIBRO
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Uni
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Somewhere
Hi Sophie Anne, and welcome.

I think that even if someone replied to you that this or that medication "does not trigger headaches" it wouldn't really help you because A) we are all different, so what works for one won't always for another, and B) if you are especially prone to that reaction, then it is possible that any such drug will give you that reaction.

You could just keep trying different ones, or you could forget medication and try something completely different. That is of course up to you. But there are a lot of things you can try to increase your overall health and help to keep depression at least somewhat at bay, and/or to manage it as best you can, things that do not involve taking any medication at all. I would suggest you try that, as it would additionally remove the weight gain.
 

Jemima

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Joined
Jul 30, 2020
Messages
508
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DX FIBRO
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11/2019
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PT
Hi Sophie Anne,

Welcome to the forum!

Others here might well chime in with positive prescription antidepressant recommendations, so I'll let them take the lead on that one. However, having also had real trouble with antidepressants, I have managed to identify alternative supplements that I'm finding work better than any prescription med I ever took - without the side effects - so I thought that might be worth a mention!

I'm not prone to migraines these days, but have found that every antidepressant I've ever tried made me really sick with things like nausea, dizziness, fatigue, hot flashes, etc. I really get the weight gain issue too - every time I've ever gone on one of those drugs it's felt as if I blink and I've gain 10kg overnight, which is about 1.5 stone. That feeling sucks! Over the years, I increasingly took it as yet another sign that my body didn't like them one bit.

I have fibro, but have also had depression for 25 years. As a silver lining to developing FM, trying to find helpful treatments finally led me to make a depression breakthrough. Particularly for depression symptoms, I take magnesium glycinate (was life-changing for me) and low-dose lithium orotate (5mg a day). For the fibro pain/angry body symptoms I take boswellia. For fog and energy I take Acetyl L-Carnitine, CoQ10, and ALA.

I know that's a crazy bunch of stuff, and also that - as Sunkacola said above - we're all different; some people here on the forum have found success with different supplements, or different lifestyle changes - like going keto for example. It seems to be a case of researching and experimenting to find what works best for you. But, if you get sick of trying different drugs from your doctor, it might be worth experimenting with the supplement route and others. For a lot of us, the right solution - to some degree at least - is just waiting around the corner!

Whatever you decide to try next, I wish you every luck in finding the relief you need, without those awful migraines. I used to get them sometimes when I was in my teens and early 20s and wow, that was horrendous. I hope they are in your rearview soon too 🤞
 

Sophie Anne

New member
Joined
Aug 20, 2021
Messages
3
Reason
DX FIBRO
Diagnosis
04/2014
Country
IR
Thanks Sunkacola..😊

I have tried a lot of SSRI anti depressants over the years with same side effects..including headache migraine trigger.

I have to be wise though as mood goes too low without same..And That is not a place that I would recommend.

Will look up Jeminas Magnesium Glycinate suggestion. Rheumatologistsuggested same but Health Shop couldnt source. i cannot tolerate CQ10 or any stimulants.
Thanks
Sophie Anne
 

Jemima

Very helpful member
Joined
Jul 30, 2020
Messages
508
Reason
DX FIBRO
Diagnosis
11/2019
Country
PT
Will look up Jeminas Magnesium Glycinate suggestion. Rheumatologistsuggested same but Health Shop couldnt source.
I buy KAL brand, which I'm pretty sure you can get on Amazon!
Whatever you do, Sophie Anne, good luck 🌻
 
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