D-ribos

Auriel

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Jun 8, 2021
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575
Reason
DX FIBRO
Diagnosis
08/2006
Country
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State
UK
Hi Rabbitmom welcome to the forum ☕🧁, I can’t say it’s a name I’m familiar with, but I like to try new things. is it available in chemists/health stores in the uk? this has come at a perfect time as my fatigue (and pain) is quite bad at the minute, I’m sure you’ll get lots more welcomes and discussions on this soon welcome again 🍭🐰🍭
 
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JayCS

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DX FIBRO
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02/2020
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GE
Hello there, Rabbitmom! Yes, I have tried many supps for fatigue, incl. D-ribose. When people wrote about it, it sometimes read like the militantly touted miracle cures such as guaifenesin, LDN etc., which seem to work perfectly for a few, but not for most. But it's cheap and easy to get and only few side effects, so worth trying. My end result: Initially it seemed a great booster, but I soon realized in the large amounts recommended it was no longer helping, but causing quite a few GI problems. I still use it before special challenges, but it's nothing more than a sort of short sugary boost, like eating chocolate or a Mars bar. Since it actually is a sugar, I'm worried it'll be bad for my general health (avoid simple carbs) and especially my lipids.
The medical evidence is only for CFS and only via an "open-label non-blinded, non-randomized, and non-crossover subjective study", so very placebo biased. It is supposed to work via mitochondria / ATP, something I'd often read and felt might be one of my problems. But it hardly helps me.
Instead and far before that I'd recommend L-carnitine, ALA, magnesium glycinate and malate, CoQ10, ginkgo and selenium, and if you've done that and want to dabble more, then like you say D-ribose as well as NAC, NADH, PQQ and SAMe.
I have a big tub of powder, of which I take about half a teaspoonful in "emergencies", praps another later.
 
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Rabbitmom

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May 4, 2022
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It's a supplement here in the U.S. so I don't know about the U.K., sorry. It's in pill form as well as powdered. I took one, 4,200 mg capsule, today. Honestly I think I had a boost of energy. But I was having a good day already. The best test is when I'm having an exhausted feeling day. I'll report back soon.
 

Auriel

Very helpful member
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Joined
Jun 8, 2021
Messages
575
Reason
DX FIBRO
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Country
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State
UK
Ok thankyou 🌟⭐💫
 

Sabina

Member
Joined
Aug 6, 2020
Messages
28
Reason
DX FIBRO
Diagnosis
09/2010
Country
US
State
IL
D-Ribose has helped me quite a bit with energy & stamina. I take 2,000-5,000 per day of the powder mixed in water. 2,000 mg per day is good for maintenance & I increase it when I know I need some extra energy for walking or travel, etc.
 

Rabbitmom

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May 4, 2022
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That's great to hear. So far for me, I'm seeing I'm taking more on bad days. Thank you for sharing your dosing.
 

JayCS

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DX FIBRO
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02/2020
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GE
OK, I'm giving up on D-ribose completely now: For me it causes a hangover, slight GI side effects and is very likely bad for my lipids.
I tried 4-5g on two 'event' days, socializing in the early evening, where I needed extra energy for 2 hours.
After getting only strange boosts from it, which only enable me to overdo it more easily, without managing to stop the aftermath,
I looked up if anyone has seen what it does for lipids and saw that at least in rats it increases liver triglycerides.
Then after thinking of overdoing it as a kind of hangover feeling, I on a hunch looked up "hangover without drinking alcohol".
On one of the first pages with many possible causes, the first thing they blamed this on is ..... sugar.
Interesting connection: Only alcohol in higher amounts increases triglycerides, in moderate to low amounts decreases them.
So - I'm provocatively simplifying: Sugar is worse for triglycerides / fatty liver than alcohol... Plus you can get hangovers from both.

So take care: Ribose is still a simple sugar, despite the fact that it occurs in our bodies and is related to ATP, which "is" our energy.
 
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