Lots of questions.
I have had no side effects at all & started at 1200 mg twice daily & felt better within days. I felt so bad initially it was unbelievable, Not sure it is possible that the guaifenisin could have made me feel any worse. I have been on Qulipta for migraines for several month before starting the guaifenisin. it is suppose to block Cgrp which is the chemical that causes migraines. It did help some …. Maybe 50% with intensity but still with really bad migraines 3 To 4 days a week.
When i get migraines -I do get this really very thick mucus That slides down the back of my throat & also I blow it from the nose. Multiple theories out there……1 is that the nasal nerve is 1 of the 5 nerves that gets pushed on by the fluid & it constantly fires creating the migraine. Other nerves are in the temples, behind the eyes, & in back of the head. causing pain in those areas. Most migraineurs have issues with multiple nerves. . I dont belive its sinusitis bc it usually clears after 3 days ( normal for migraines) "& I have been to multiple docs and once in my life have had a sinus infection. But who knows……. I am certain guaifenisin keeps that mucus thinned Which could prevent the migraines itself. About the mucus…..a néw type of mri last year found that migraine patients get fluid in the peri vascular spaces around blood vessels in the brain. those spaces are created by fluid that wasn’t cleared away by the body’ s brain draining system. The theories go that this also what causes dementia, Parkinsonism, ms, etc. Next …. guaifenisin is also a muscle relaxant help relaxing the muscles of the body which could also keep the muscle spasmsfrom compressing the nerves causing pain. Which again could prevent a migraine. Then lastly the guaifenisin protocol says it lowers the accumulated phosphorus in tissues. So, the levels of phosphorus in blood could still be normal. I have never had a tissue biopsy to check those levels. So, I don’t know about that. Maybe it’s a combo of multiple things. But for now I am enjoying waking up almost every day with no headache, no neck & shoulder pain. For me it has been a godsend with no side effects & honestly I dont care how it works bc I am almost pain free every day, i
posted on here just in case it could help other people like it has me! Good luck to you.