- Apr 2, 2021
- DX FIBRO
Sorry, I meant Pregbalin was the one they have complained about to me as being expensive and coming up in "red". It made me feel like I was an inconvenience and costing them money. It's not the first time they've dug something up and complained to my face. I answer back politely that this is the way things are, what I'm doing to help myself and that I wouldn't speak to them unless I needed help. Since before the lockdown I've made a point of keeping my distance.Which one did they mean? I'd think pregabalin in comparison to amitriptyline, which is cheap, maybe an 20% or less of pregabalin. But of course that very much depends on the doses, which (see the cost-efficiency studies) are different according to our body, conditions (esp. fibro), symptoms & body, as well as many other factors like other meds, total health care costs and sick leave. What's the sense of a cheaper med that helps less and harms more... - it'll only cause costs elsewhere.
Trying to understand why gabapentin (now not amitriptyline like above) is prescribed so often, I just looked for a price comparison and found rheumatologyadvisor citing a study saying:
"For patients with peripheral neuropathic pain (PNP), the adjusted cost per patient is lower for treatment with pregabalin than gabapentin."
So pregabalin doesn't seem that much more expensive than gabapentin for the insurance/us (the payer), and all factors considered maybe less expensive, at least for society/employer.
"The researchers found that the duration of treatment was slightly shorter for pregabalin than gabapentin (5.2 vs 5.5 months; P= .124), with mean doses of 227.4 mg and 900 mg, respectively. Per patient, the average study drug cost was higher for pregabalin than gabapentin (€214.6 vs €157.4: P< .001), although there was a lower cost of concomitant analgesic medication (€176.5 vs €306.7; P< .001)"
"Per patient, the adjusted average total cost was lower for pregabalin treatment (€2,413 vs €3,201; P= .002) because of significantly lower health care costs and non-health care costs; this was due to lower use of concomitant medications, fewer primary care visits, and fewer days of sick leave.
“After loss of exclusivity of both drugs, pregabalin continued to show lower health care and non-health care costs than gabapentin in the treatment of PNP in routine clinical practice,” the authors write.
Several of the researchers have to do with Pfizer, who makes pregabalin. However it doesn't seem to me that much more expensive.