I know they don't take away all the pain. And I know that I will probably always wish someone could explain why some days I can do a lot and be much better than other days where I do much less, yet still have pain. For me the nerve pain that feels like someone is sticking a lot of hot pins and needles in me and leaving them in as well as taking hot sandpaper and rubbing me. Lyrica helps a lot with that but I still feel it at times. I especially get that in my upper arms on days when I have used my arms a lot. (not diabetic, which is a common question I get). and what I think are migraines are another of the worst type of pain. I wish that if we are stuck with chronic pain diseases, at least everyone would respond to medicines instead of them doing nothing for some people or causing more severe side effects for other people. My worst fibromyalgia symptoms are the migraines, eye problems (stinging and dry), nerve pain from repetitive use of arms, and other pains that fall under being annoying only because they are milder than the more severe pains.