I have severe muscle twitching. Legs, arms, butt, even sometimes my head - that is the weirdest feeling ever. My muscle fatigue and cramping are horrible and I am on Cyclobenzaprine (muscle relaxer). My fingers even pull into the palms of my hand on their own. I had EMG, MRI, bloodwork, etc. Told it's my fibro and they upped my meds from the 1/2 pill I was taking to a whole one.