Has anyone taken Vicodin and noticed a dramatic decrease in their fatigue? I took it because I was having a very bad arthritis flare up and noticed that I had so much energy! I also noticed this energy when I took my vicodin after surgery, as well. I talked to my rheumatologist and she told me that it is very common for people with fibromyalgia to be energized by vicodin. Too bad it's a narcotic because I feel like I could clean the whole house and do a million different things when I take it. It is so tempting to take it more often than I need for pain just so I can get the energizing effects. But I don't. Tonight, I called in to work because I was just so dang tired and I couldn't bare being oriented by a girl who doesn't even want me to be there (I'm a new nurse). It is only a PRN job so I'm not worried about getting fired or anything but dang! I should have just took a vicodin and got me some Starbucks and kept on trucking.